Molecular Details
DICL_CP_0311573
- 10H-phenothiazine
Basic Molecular Information
Basic Information
DICL ID
DICL_CP_0311573
PubChem CID
Molecular Formula
C12H9NS Molecular Weight
199.278 g/mol
Synonyms/Alias
[PHENOTHIAZINE; 10H-Phenothiazine; 92-84-2; Thiodiphenylamine; Contaverm; Dibenzo-1;4-thiazine; Fenoverm; Phenosan; Feeno; Dibenzothiazine; Phenthiazine; Nemazine; Agrazine; Antiverm; Fentiazin; Helme...
InChI Key
WJFKNYWRSNBZNX-UHFFFAOYSA-N
InChI
InChI=1S/C12H9NS/c1-3-7-11-9(5-1)13-10-6-2-4-8-12(10)14-11/h1-8,13H
IUPAC Name
10H-phenothiazine
CAS Number
92-84-2
Structure Information
Chemical Structure Visualization
SMILES Notation
2D Molecular Drawing
Carbon (C)
Hydrogen (H)
Oxygen (O)
Nitrogen (N)
Sulfur (S)
SDF
23 25 0 0 0 0 0 0 0 0999 V2000
3.4640 0.8064 -0.4929 C 0 0 0 0 0 0 0 0 0 0 0 0
3.5392 -0.5613 -0.7728 C 0 0 0 0 0 0 0 0 0 0 0 0
2.4889 -1.409...
Experimental Data
Activity Data
Target Ion Channel
Two-pore channel subunit TPC2
Uniprot Accession Number
Function
Inactive
Species
Homo sapiens (Human)
IC50
N/A (Not available)
EC50
N/A (Not available)
Ki
N/A (Not available)
Kd
N/A (Not available)
Inhibition
No effect
Experimental Conditions
pH
pH 7.4
Holding Potential
Not specified
Temperature
37 °C
Test Method
Fluorometric Imaging Plate Reader (FLIPR) Membrane Potential Assay
Test Species
HEK293 cell (Homo sapiens embryonic kidney 293 cell)
Binding Information
Binding Site
Not specified
Binding Site Residue
Not specified
Disease Information
Related Disease
Not specified
References
Computed Properties
Heavy Atom Count
14
Rotatable Bonds
0
logP
3.8948
Complexity
60.2897
TPSA (Ų)
12.03
H-Bond Donors
1
H-Bond Acceptors
2
Ring Count
3